Abstract,Author,DOI,ISSN,Journal issue,Journal title,Pagination,Preprint/Postprint,Publication title,Publication type,Publisher,Volume,Year
"Introduction  Our objective was to assess abnormalities of the odontoid-hip axis (OD-HA) angle in a mild scoliotic population to determine whether screening for malalignment would help predict the distinction between progressive and stable adolescent idiopathic scoliosis (AIS) at early stage.  Materials and methods All patients (non-scoliotic and AIS) underwent a biplanar X-ray between 2013 and 2020. In AIS, inclusion criteria were Cobb angle between 10° and 25°; Risser sign lower than 3; age higher than 10 years; and no previous treatment. A 3D spine reconstruction was performed, and the OD-HA was computed automatically. A reference corridor for OD-HA values in non-scoliotic subjects was calculated as the range [5th–95th percentiles]. A severity index, helping to distinguish stable and progressive AIS, was calculated and weighted according to the OD-HA value.  Results Eighty-three non-scoliotic and 205 AIS were included. The mean coronal and sagittal OD-HA angles in the non-scoliotic group were 0.2° and −2.5°, whereas in AIS values were 0.3° and −0.8°, respectively. For coronal and sagittal OD-HA, 27.5% and 26.8% of AIS were outside the reference corridor compared with 10.8% in non-scoliotic (OR = 3.1 and 3). Adding to the severity index a weighting factor based on coronal OD-HA, for thoracic scoliosis, improved the positive predictive value by 9% and the specificity by 13%.  Conclusion Analysis of OD-HA suggests that AIS patients are almost three times more likely to have malalignment compared with a non-scoliotic population. Furthermore, analysis of coronal OD-HA is promising to help the clinician distinguish between stable and progressive thoracic scoliosis.","LANGLAIS, Tristan||VERGARI, Claudio||ROUGEREAU, Grégoire||GAUME, Mathilde||GAJNY, Laurent||ABELIN-GENEVOIS, Kariman||BERNARD, Jean-Claude||HU, Zongshan||CHENG, Jack Chun Yiu||CHU, Winnie Chiu Wing||ASSI, Ayman||KARAM, Mohamad||GHANEM, Ismat||BASSANI, Tito||SCONFIENZA, Luca Maria||GALBUSERA, Fabio||BRAYDA-BRUNO, Marco||COURTOIS, Isabelle||EBERMEYER, Eric||VIALLE, Raphaël||DUBOUSSET, Jean||SKALLI, Wafa","10.1007/s00586-024-08178-w","0940-6719","4","European Spine Journal","1665-1674","Post-print","Assessment of malalignment at early stage in adolescent idiopathic scoliosis: a longitudinal cohort study","Article dans une revue avec comité de lecture",,"33","2024"
"Purpose 	To validate the predictive power and reliability of a novel quasi-automatic method to calculate the severity index of adolescent idiopathic scoliosis (AIS). Methods 	Fifty-five AIS patients were prospectively included (Age: 10-15, Cobb: 16° ± 4°). Patients underwent low-dose biplanar x-rays and a novel fast method for 3D reconstruction of the spine was performed. They were followed until skeletal maturity (stable patients) or brace prescription (progressive patients). The severity index was calculated at the first exam, based on 3D parameters of the scoliotic curve, and it was compared with the patient’s final outcome (progressive or stable). Three operators have repeated the 3D reconstruction twice for a subset of 30 patients to assess reproducibility (through Cohen’s kappa and intraclass correlation coefficient). Results 	85% of the patients were correctly classified as stable or progressive by the severity index, with a sensitivity of 92% and specificity of 74%. Substantial intra-operator agreement and good inter-operator agreement were observed, with 80% of the progressive patients correctly detected at the first exam. The novel severity index assessment took less than 4 minutes of operator time. Conclusions 	The fast and semi-automatic method for 3D reconstruction developed in this work allowed for a fast and reliable calculation of the severity index. The method is fast and user friendly. Once extensively validated, this severity index could allow very early initiation of conservative treatment for progressive patients, thus increasing treatment efficacy and therefore reducing the need for corrective surgery.","COURTOIS, Isabelle||EBERMEYER, Eric||ABELIN-GENEVOIS, Kariman||KIM, Youngwoo||LANGLAIS, Tristan||VIALLE, Raphaël||ASSI, Ayman||GHANEM, Ismat||DUBOUSSET, Jean||SKALLI, Wafa||GAJNY, Laurent||VERGARI, Claudio","10.1007/s00586-019-05998-z","0940-6719",,"European Spine Journal","1-7","Post-print","Quasi-automatic early detection of progressive idiopathic scoliosis from biplanar radiography: a preliminary validation","Article dans une revue avec comité de lecture","Springer Verlag",,"2019"
