https://sam.ensam.eu:443 The DSpace digital repository system captures, stores, indexes, preserves, and distributes digital research material. Sat, 11 Jul 2026 03:14:49 GMT 2026-07-11T03:14:49Z http://hdl.handle.net/10985/18182 Reliable Protocol for Shear Wave Elastography of Lower Limb Muscles at Rest and During Passive Stretching. DUBOIS, Guillaume; KHEIREDDINE, Walid; BONNEAU, Dominique; THOREUX, Patricia; TANTER, Mickael; GENNISSON, Jean-Luc; SKALLI, Wafa; ROUCH, Philippe; VERGARI, Claudio Development of shear wave elastography gave access to non-invasive muscle stiffness assessment in vivo. The aim of the present study was to define a measurement protocol to be used in clinical routine for quantifying the shear modulus of lower limb muscles. Four positions were defined to evaluate shear modulus in 10 healthy subjects: parallel to the fibers, in the anterior and posterior aspects of the lower limb, at rest and during passive stretching. Reliability was first evaluated on two muscles by three operators; these measurements were repeated six times. Then, measurement reliability was compared in 11 muscles by two operators; these measurements were repeated three times. Reproducibility of shear modulus was 0.48 kPa and repeatability was 0.41 kPa, with all muscles pooled. Position did not significantly influence reliability. Shear wave elastography appeared to be an appropriate and reliable tool to evaluate the shear modulus of lower limb muscles with the proposed protocol. Thu, 01 Jan 2015 00:00:00 GMT http://hdl.handle.net/10985/18182 2015-01-01T00:00:00Z DUBOIS, Guillaume KHEIREDDINE, Walid BONNEAU, Dominique THOREUX, Patricia TANTER, Mickael GENNISSON, Jean-Luc SKALLI, Wafa ROUCH, Philippe VERGARI, Claudio Development of shear wave elastography gave access to non-invasive muscle stiffness assessment in vivo. The aim of the present study was to define a measurement protocol to be used in clinical routine for quantifying the shear modulus of lower limb muscles. Four positions were defined to evaluate shear modulus in 10 healthy subjects: parallel to the fibers, in the anterior and posterior aspects of the lower limb, at rest and during passive stretching. Reliability was first evaluated on two muscles by three operators; these measurements were repeated six times. Then, measurement reliability was compared in 11 muscles by two operators; these measurements were repeated three times. Reproducibility of shear modulus was 0.48 kPa and repeatability was 0.41 kPa, with all muscles pooled. Position did not significantly influence reliability. Shear wave elastography appeared to be an appropriate and reliable tool to evaluate the shear modulus of lower limb muscles with the proposed protocol. http://hdl.handle.net/10985/8274 Intervertebral disc characterization by shear wave elastography: an in-vitro preliminary study VERGARI, Claudio; ROUCH, Philippe; DUBOIS, Guillaume; BONNEAU, Dominique; DUBOUSSET, Jean; TANTER, Mickael; GENNISSON, Jean-Luc; SKALLI, Wafa Patient-specific numerical simulation of the spine is a useful tool both in clinic and research. While geometrical personalization of the spine is no more an issue, thanks to recent technological advances, non-invasive personalization of soft tissue’s mechanical properties remains a challenge. Ultrasound elastography is a relatively recent measurement technique allowing the evaluation of soft tissue’s elastic modulus through the measurement of shear wave speed (SWS). The aim of this study was to determine the feasibility of elastographic measurements in intervertebral disc (IVD). An in-vitro approach was chosen to test the hypothesis that SWS can be used to evaluate IVD mechanical properties and to assess measurement repeatability. Eleven oxtail IVDs were tested in compression to determine their stiffness and apparent elastic modulus at rest and at 400 N. Elastographic measurements were performed in these two conditions and compared to these mechanical parameters. The protocol was repeated six times to determine elastographic measurement repeatability. Average SWS over all samples was 5.3 ± 1.0 m/s, with a repeatability of 7 % at rest and 4.6 % at 400 N; stiffness and apparent elastic modulus were 266.3 ± 70.5 N/mm and 5.4 ± 1.1 MPa at rest, respectively, while at 400 N they were 781.0 ± 153.8 N/mm and 13.2 ± 2.4 MPa. Correlations were found between elastographic measurements and IVD mechanical properties; these preliminary results are promising for further in-vivo application. Wed, 01 Jan 2014 00:00:00 GMT http://hdl.handle.net/10985/8274 2014-01-01T00:00:00Z VERGARI, Claudio ROUCH, Philippe DUBOIS, Guillaume BONNEAU, Dominique DUBOUSSET, Jean TANTER, Mickael GENNISSON, Jean-Luc SKALLI, Wafa Patient-specific numerical simulation of the spine is a useful tool both in clinic and research. While geometrical personalization of the spine is no more an issue, thanks to recent technological advances, non-invasive personalization of soft tissue’s mechanical properties remains a challenge. Ultrasound elastography is a relatively recent measurement technique allowing the evaluation of soft tissue’s elastic modulus through the measurement of shear wave speed (SWS). The aim of this study was to determine the feasibility of elastographic measurements in intervertebral disc (IVD). An in-vitro approach was chosen to test the hypothesis that SWS can be used to evaluate IVD mechanical properties and to assess measurement repeatability. Eleven oxtail IVDs were tested in compression to determine their stiffness and apparent elastic modulus at rest and at 400 N. Elastographic measurements were performed in these two conditions and compared to these mechanical parameters. The protocol was repeated six times to determine elastographic measurement repeatability. Average SWS over all samples was 5.3 ± 1.0 m/s, with a repeatability of 7 % at rest and 4.6 % at 400 N; stiffness and apparent elastic modulus were 266.3 ± 70.5 N/mm and 5.4 ± 1.1 MPa at rest, respectively, while at 400 N they were 781.0 ± 153.8 N/mm and 13.2 ± 2.4 MPa. Correlations were found between elastographic measurements and IVD mechanical properties; these preliminary results are promising for further in-vivo application. http://hdl.handle.net/10985/11884 Lumbar annulus fibrosus biomechanical characterization in children by ultrasound shear wave elastography DUBOIS, Guillaume; GENNISSON, Jean-Luc; TANTER, Mickael; DUBOUSSET, Jean; SKALLI, Wafa; VIALLE, Raphaël; ROUCH, Philippe; VERGARI, Claudio Objectives Intervertebral disc (IVD) is key to spine biomechanics, and it is often involved in the cascade leading to spinal deformities such as idiopathic scoliosis, especially during the growth spurt. Recent progress in elastographic techniques allowed access to noninvasively measure cervical IVD in adults; the aim of this study was to determine the feasibility and reliability of shear wave elastography in healthy children lumbar IVD. Methods Elastographic measurements were performed in thirty-one healthy children (6 to 17 years old), in the annulus fibrosus and in the transverse plane of L5-S1 or L4-L5 IVD. Reliability was determined by 3 experienced operators repeating measurements. Results Average shear wave speed in IVD was 2.9 ± 0.5 m/s; no significant correlations were observed with sex, age or body morphology. Intra-operator repeatability was 5.0 % while inter-operator reproducibility was 6.2 %. Intraclass correlation coefficient was higher than 0.9 for each operator. Conclusions Feasibility and reliability of IVD shear wave elastography was demonstrated. The measurement protocol is compatible with the clinical routine, and the results show the potential to give an insight into spine deformity progression and early detection. Fri, 01 Jan 2016 00:00:00 GMT http://hdl.handle.net/10985/11884 2016-01-01T00:00:00Z DUBOIS, Guillaume GENNISSON, Jean-Luc TANTER, Mickael DUBOUSSET, Jean SKALLI, Wafa VIALLE, Raphaël ROUCH, Philippe VERGARI, Claudio Objectives Intervertebral disc (IVD) is key to spine biomechanics, and it is often involved in the cascade leading to spinal deformities such as idiopathic scoliosis, especially during the growth spurt. Recent progress in elastographic techniques allowed access to noninvasively measure cervical IVD in adults; the aim of this study was to determine the feasibility and reliability of shear wave elastography in healthy children lumbar IVD. Methods Elastographic measurements were performed in thirty-one healthy children (6 to 17 years old), in the annulus fibrosus and in the transverse plane of L5-S1 or L4-L5 IVD. Reliability was determined by 3 experienced operators repeating measurements. Results Average shear wave speed in IVD was 2.9 ± 0.5 m/s; no significant correlations were observed with sex, age or body morphology. Intra-operator repeatability was 5.0 % while inter-operator reproducibility was 6.2 %. Intraclass correlation coefficient was higher than 0.9 for each operator. Conclusions Feasibility and reliability of IVD shear wave elastography was demonstrated. The measurement protocol is compatible with the clinical routine, and the results show the potential to give an insight into spine deformity progression and early detection. http://hdl.handle.net/10985/8795 Non-invasive biomechanical characterization of intervertebral discs by shear wave ultrasound elastography: a feasibility study DUBOIS, Guillaume; BONNEAU, Dominique; DUBOUSSET, Jean; TANTER, Mickael; GENNISSON, Jean-Luc; ROUCH, Philippe; VERGARI, Claudio Objectives Although magnetic resonance is widely spread to assess qualitatively disc morphology, a simple method to determine reliably intervertebral disc status is still lacking. Shear wave elastography is a novel technique that allows quantitative evaluation of soft-tissues’ mechanical properties. The aim of this study was to assess preliminary the feasibility and reliability of mechanical characterization of cervical intervertebral discs by elastography and to provide first reference values for asymptomatic subjects. Methods Elastographic measurements were performed to determine shear wave speed (SWS) in C6-C7 or C7-T1 disc of 47 subjects; repeatability and inter-operator reproducibility were assessed. Results Global average shear wave speed (SWS) was 3.0 ± 0.4 m/s; measurement repeatability and inter-user reproducibility were 7 and 10 %, respectively. SWS was correlated with both subject’s age (p = 1.3 × 10−5) and body mass index (p = 0.008). Conclusions Shear wave elastography in intervertebral discs proved reliable and allowed stratification of subjects according to age and BMI. Applications could be relevant, for instance, in early detection of disc degeneration or in follow-up after trauma; these results open the way to larger cohort studies to define the place of this technique in routine intervertebral disc assessment. Key Points • A simple method to obtain objectively intervertebral disc status is still lacking • Shear wave elastography was applied in vivo to assess intervertebral discs • Elastography showed promising results in biomechanical disc evaluation • Elastography could be relevant in clinical routine for intervertebral disc assessment Wed, 01 Jan 2014 00:00:00 GMT http://hdl.handle.net/10985/8795 2014-01-01T00:00:00Z DUBOIS, Guillaume BONNEAU, Dominique DUBOUSSET, Jean TANTER, Mickael GENNISSON, Jean-Luc ROUCH, Philippe VERGARI, Claudio Objectives Although magnetic resonance is widely spread to assess qualitatively disc morphology, a simple method to determine reliably intervertebral disc status is still lacking. Shear wave elastography is a novel technique that allows quantitative evaluation of soft-tissues’ mechanical properties. The aim of this study was to assess preliminary the feasibility and reliability of mechanical characterization of cervical intervertebral discs by elastography and to provide first reference values for asymptomatic subjects. Methods Elastographic measurements were performed to determine shear wave speed (SWS) in C6-C7 or C7-T1 disc of 47 subjects; repeatability and inter-operator reproducibility were assessed. Results Global average shear wave speed (SWS) was 3.0 ± 0.4 m/s; measurement repeatability and inter-user reproducibility were 7 and 10 %, respectively. SWS was correlated with both subject’s age (p = 1.3 × 10−5) and body mass index (p = 0.008). Conclusions Shear wave elastography in intervertebral discs proved reliable and allowed stratification of subjects according to age and BMI. Applications could be relevant, for instance, in early detection of disc degeneration or in follow-up after trauma; these results open the way to larger cohort studies to define the place of this technique in routine intervertebral disc assessment. Key Points • A simple method to obtain objectively intervertebral disc status is still lacking • Shear wave elastography was applied in vivo to assess intervertebral discs • Elastography showed promising results in biomechanical disc evaluation • Elastography could be relevant in clinical routine for intervertebral disc assessment