Fracture characterization in cancellous bone specimens via surface difference evaluation of 3D registered pre- and post-compression micro-CT scans
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In recent years, increasingly stringent passenger vehicle safety requirements have led to a renewed interest in the fracture properties of bone. It has been shown that can- cellous bone architecture is strongly linked to its overall behavior (Follet et al. 2011; Prot et al. 2015). Micro- fracture mechanisms have been resolved by time- consuming direct microscopy (Prot et al. 2012) or by the use of calcein (Lambers et al. 2014; Hernandez et al. 2014). Furthermore, the application of CT scanners, along with the development of registration algorithms, has allowed separated portions of fractured specimen to be registered to the pre-compression scan so as to quantify the differ- ence between 3D shapes as a mean to characterize the fracture behavior (Tassani & Matsopoulos 2014). How- ever, this method is operator-dependent in the case of multiple fracture zone identification and requires suffi- cient deformation of the specimen to obtain distinct reg- istration sets. In addition, built-in micro-compression testers, developed by CT scanner manufacturers, are limited to loading at low levels of strain rate, which does not allow measurement over a range that is representative of daily life. The goal of this study was to identify distinct fracture patterns based on micro-CT scans of cancellous bone specimens, loaded over a large range of strain rates, without the need for specimens that have broken into separate pieces.
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PROT, Marianne; CLOETE, Trevor John; SALETTI, Dominique; LAPORTE, Sébastien (Taylor and Francis, 2014)Not applicable
The behavior of cancellous bone from quasi-static to dynamic strain rates with emphasis on the intermediate regime PROT, Marianne; CLOETE, Trevor John; SALETTI, Dominique; LAPORTE, Sébastien (Elsevier, 2016)Previous studies, conducted using quasi-static and dynamic compression tests, have shown that the mechanical strength of cancellous bone is strain rate dependent. However, these studies have not included the intermediate ...
DUBOIS, Guillaume; PROT, Marianne; LAPORTE, Sébastien; CLOETE, Trevor John (Taylor & Francis, 2015)The study of the bone fracture is an important issue for oste- oporosis and car safety. The behavior of cancellous bone is strongly linked to the micro-architecture, the strain rate (Prot et al. 2015), and the specimen ...
Links between microstructural properties of cancellous bone and its mechanical response to different strain rates. PROT, Marianne; SALETTI, Dominique; PATTOFATTO, Stéphane; BOUSSON, Valérie; LAPORTE, Sébastien (Taylor and Francis, 2013)Not applicable
PROT, Marianne; SALETTI, Dominique; LAPORTE, Sébastien; PATTOFATTO, Stéphane; BOUSSON, Valérie (2014)Previous studies showed that in vivo evaluation of the fracture risk of cancellous bone can be assessed by identifying the relationships between its microarchitecture description extracted from clinical imaging and its ...