Institut de Biomécanique Humaine Georges Charpak (IBHGC)

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L'Institut de Biomécanique Humaine Georges Charpak fait suite au Laboratoire de Biomécanique (LBM) de l’ENSAM crée en 1979 et est situé sur le Campus parisien d’ARTS ET MÉTIERS ParisTech. .

L'Institut est certifié ISO 9001 depuis le 27 juillet 2009 dans un périmètre couvrant Recherche, Formation, Relations Industrielles et Valorisation. La recherche partenariale ou les prestations de valorisation sont gérées dans le cadre de l'Institut Carnot ARTS.

Voir le site du laboratoire :
http://biomecanique.ensam.eu/

Recent Submissions

A numerical model suggests the interplay between nuclear plasticity and stiffness during a perfusion assay

DEVERAUX, Solenne; ALLENA, Rachele; AUBRY, Denis (Elsevier, 2017)

Cell deformability is a necessary condition for a cell to be able to migrate, an ability that is vital both for healthy and diseased organisms. The nucleus being the largest and stiffest organelle, it often is a barrier ...
Mechanical modelling of confined cell migration across constricted-curved micro-channels

ALLENA, Rachele (Tech Science Press, 2014)

Confined migration is a crucial phenomenon during embryogenesis, immune response and cancer. Here, a two-dimensional finite element model of a HeLa cell migrating across constricted-curved micro-channels is proposed. The ...
Heterogeneous directions of orthotropy in three-dimensional structures: finite element description based on diffusion equations

ALLENA, Rachele; CLUZEL, Christophe (International Research Center for the Mathematics and Mechanics of Complex Systems - Università Dell’Aquila, Italy, 2018)

Heterogeneous materials such as bone or woven composites show mesostructures whose constitutive elements are all oriented locally in the same direction and channel the stress flow throughout the mechanical structure. The ...
A Coupled Friction-Poroelasticity Model of Chimneying Shows that Confined Cells Can Mechanically Migrate Without Adhesions

MONDESERT-DEVERAUX, Solenne; ALLENA, Rachele; AUBRY, Denis (Tech Science Press, 2018)

Cell migration is the cornerstone of many biological phenomena such as cancer metastasis, immune response or organogenesis. Adhesion-based motility is the most renown and examined motility mode, but in an adhesion-free ...
A general method for the determination of the local orthotropic directions of heterogeneous materials: application to bone structures using µCT images

CLUZEL, Christophe; ALLENA, Rachele (International Research Center for the Mathematics and Mechanics of Complex Systems - Università Dell’Aquila, Italy, 2018)

To assess the degree (i.e., isotropy, transverse isotropy, or orthotropy) and the directions of anisotropy of a three-dimensional structure, information about its mesostructure is necessary. Usually, a topological analysis ...
The discriminant role of mechanics during cell migration

ALLENA, Rachele (Elsevier, 2018)

Cell migration is a fundamental process involved in many mechanobiological phenomena such immune response, bone remodelling and tumorogenesis. During the last decades several numerical works have been proposed in the ...
Cell nutriments and motility for mechanobiological bone remodeling in the context of orthodontic periodontal ligament deformation

GEORGE, Daniel; ALLENA, Rachele; REMOND, Yves (Elsevier, 2018)

Bone remodeling is a complex phenomenon during which old and new bone is continuously removed and replaced. This phenomenon involves several processes at different length scales such as mechanical, biological, molecular, ...