The effect of viscoelasticity in an airway closure model
Article dans une revue avec comité de lecture
Auteur
ROMANO, FrancescoMURADOGLU, M.FUJIOKA, H.GROTBERG, J.B.Résumé
Abstract
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Article dans une revue avec comité de lecture;ROMANO, Francesco; ; (Cambridge University Press (CUP), 2022-01)
Capillary instability of a two-layer liquid film lining a rigid tube is studied computationally as a model for liquid plug formation and closure of human airways. The two-layer liquid consists of a serous layer, also called ...
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Article dans une revue avec comité de lecture(American Physical Society, 2019)The closure of a human lung airway is modeled as an instability of a two-phase flow in a pipe coated internally with a Newtonian liquid. For a thick enough coating, the Plateau-Rayleigh instability creates a liquid plug ...
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Article dans une revue avec comité de lecture; ; ; ;ROMANO, Francesco; (American Physical Society (APS), 2023-05)
Airway mucus is a complex material with both viscoelastic and viscoplastic properties that vary with healthy and pathological conditions of the lung. In this study, the effects of these conditions on airway closure are ...
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Article dans une revue avec comité de lecture;HAMIDOUCHE, Souria; MOAZZEN, Masoud; ; ; ; ; ROMANO, Francesco (Elsevier BV, 2022-02)
The propagation and rupture of mucus plugs in human lungs is investigated experimentally by injecting synthetic mucus in a pre-wetted capillary tube. The rheology of our test liquid is thoroughly characterized, and four ...
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Article dans une revue avec comité de lectureROMANO, Francesco; ; (American Physical Society (APS), 2022-09)
A model of the bronchioles lined by the airway surface liquid is employed to investigate the Plateau-Rayleigh instability that can lead to the occlusion of the airways. This physiologically relevant phenomenon is normally ...