Monitoring trabecular bone microdamage using a dynamic acousto-elastic testing method
TypeArticles dans des revues avec comité de lecture
Dynamic acousto-elastic testing (DAET) is based on the coupling of a lowfrequency (LF) acoustic wave and high-frequency ultrasound (US) pulses (probing wave). It was developed to measure US viscoelastic and dissipative non-linearity in trabecular bone. It is well known that this complex biphasic medium contains microdamage, even when tissues are healthy. The purpose of the present study was to assess the sensitivity of DAET to monitor microdamage in human calcanei. Three protocols were therefore performed to investigate the regional heterogeneity of the calcaneus, the correlation between DAET measurements and microdamage revealed by histology, and DAET sensitivity to mechanically induced fatigue microdamage. The non-linear elastic parameter b was computed for all these protocols. The study demonstrated the presence of high viscoelastic and dissipative non-linearity only in the region of the calcaneus close to the anterior talocalcaneal articulation (region of high bone density). Protocols 1 and 2 also showed that most unsorted calcanei did not naturally exhibit high non-linearity, which is correlated with a low level of microcracks. Nevertheless, when microdamage was actually present, high levels of US non-linearity were always found, with characteristic non-linear signatures such as hysteresis and tension/compression asymmetry. Finally, protocol 3 demonstrated the high sensitivity of DAET measurement to fatigue-induced microdamage.
Cette publication figure dans le(s) laboratoire(s) suivant(s)
Visualiser des documents liés par titre, auteur, créateur et sujet.
GUERARD, Sandra; CHEVALIER, Yann; MORESCHI, Hélène; DEFONTAINE, Marielle; CALLE, Samuel; MITTON, David (sage, 2011)For various applications, precision of the Young’s modulus of cancellous bone specimens is needed. However, measurement variability is rarely given. The aim of this study was to assess the Young’s modulus repeatability ...
HAUPERT, Sylvain; GUERARD, Sandra; MITTON, David; PEYRIN, Françoise; LAUGIER, Pascal (Acoustical Society of America, 2012)Accumulation of bone microdamage is suspected to lead to severe impairment of mechanical properties with an increase in skeletal fragility and fracture risk. The objective of the study was to evaluate the sensitivity of ...
Quantification of nonlinear elasticity for the valuation of submillimeter crack length in cortical bone HAUPERT, Sylvain; GUERARD, Sandra; MITTON, David; PEYRIN, Françoise; LAUGIER, Pascal (elsevier, 2015)The objective of this study was to investig ate the sensitivity of the nonlinear elastic properties of cortical bon e to the presence of a single submillime tric crac k. Nonli near elasticity was measured by nonlinear ...
GUERARD, Sandra; MANASSERO, Mathieu; VIATEAU, Véronique; MIGONNEY, Véronique; SKALLI, Wafa; MITTON, David (techno-press, 2014)This study aimed to assess the biomechanical performance of a new generation of artificial ligament, which can be considered “bioactive” and “biointegrated,” implanted in sheep. Thirty sheep were implanted: 15 sheep received ...
Non Destructive Characterization of Cortical Bone MicroDamage by Nonlinear Resonant Ultrasound Spectroscopy HAUPERT, Sylvain; GUERARD, Sandra; PEYRIN, Françoise; MITTON, David; LAUGIER, Pascal (PlosOne, 2014)The objective of the study was to evaluate the ability of a nonlinear ultrasound technique, the so-called nonlinear resonant ultrasound spectroscopy (NRUS) technique, for detecting early microdamage accumulation in cortical ...