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Long term evolution of bone reconstruction with bone graft substitutes

Article dans une revue avec comité de lecture
Auteur
MARTYNENKO, Oleksander V.
303089 V.N. Karazin Kharkiv National University [KhNU]
ALLENA, Rachele
466360 Institut de Biomecanique Humaine Georges Charpak
ZOLOCHEVSKY, O. O.
451229 Kharkiv Polytechnic Institute

URI
http://hdl.handle.net/10985/17442
Date
2017
Journal
The Journal of V. N. Karazin Kharkiv National University, series "Medicine"

Résumé

The review involves clinical and experimental data, constitutive modeling, and computational investigations towards an understanding on how mechanical cyclic loads for long periods of time affect damage evolution in a reconstructed bone, as well as, lifetime reduction of bone graft substitutes after advanced core decompression. The outcome of the integrated model discussed in this paper will be how damage growth in femur after advanced core decompression subjected to mechanical cyclic loading under creep and fatigue conditions may be controlled in order to optimize design and processing of bone graft substitutes, and extend lifetime of bone substitutes.

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Nom:
IBHGC_JKKNUSM_2017_ALLENA.pdf
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1.032Mo
Format:
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  • Institut de Biomécanique Humaine Georges Charpak (IBHGC)

Documents liés

Visualiser des documents liés par titre, auteur, créateur et sujet.

  • Mechanical modelling of confined cell migration across constricted-curved micro-channels 
    Article dans une revue avec comité de lecture
    ALLENA, Rachele (Tech Science Press, 2014)
    Confined migration is a crucial phenomenon during embryogenesis, immune response and cancer. Here, a two-dimensional finite element model of a HeLa cell migrating across constricted-curved micro-channels is proposed. The ...
  • Simulating the Remodelling of Bone around Implants 
    Communication sans acte
    FRAME, Jamie C.; CORTÉ, Laurent; ALLENA, Rachele; ccROHAN, Pierre-Yves (2017)
    Introduction Improper osseointegration of implants leading to poor mechanical anchoring or embrittlement of neighboring bone is a major concern in orthopedic surgery [1?]. This integration is known to depend on the complex ...
  • A mechanical model to investigate the role of the nucleus during confined cell migration 
    Article dans une revue avec comité de lecture
    ALLENA, Rachele; THIAM, Hui; PIEL, Mathieu; AUBRY, Denis (Taylor & Francis, 2015)
    1. Introduction Cell migration in confinement plays a fundamental role in biological processes such as embryogenesis, immune response and tumorogenesis. Specifically, tumor cells continuously adapt their migratory ...
  • Group Creativity in Biomedical Engineering Education 
    Communication sans acte
    BOURGEOIS-BOUGRINE, Samira; ccSANDOZ, Baptiste; ALLENA, Rachele; DALLEZ, Barbara (2015)
    Aim: The present study focuses on a group creativity approach tested during a 5-day interdisciplinary seminar involving 12 members of the teaching team, a creativity facilitator and 87 students from various nationalities ...
  • A general method for the determination of the local orthotropic directions of heterogeneous materials: application to bone structures using µCT images 
    Article dans une revue avec comité de lecture
    CLUZEL, Christophe; ALLENA, Rachele (International Research Center for Mathematics & Mechanics of Complex Systems (M&MoCS),University of L’Aquila in Italy, 2018)
    To assess the degree (i.e., isotropy, transverse isotropy, or orthotropy) and the directions of anisotropy of a three-dimensional structure, information about its mesostructure is necessary. Usually, a topological analysis ...

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