A Nano-Dose Protocol For Cobb Angle Assessment in Children With Scoliosis: Results of a Phantom-based and Clinically Validated Study
Article dans une revue avec comité de lecture
STUDY DESIGN: This was a prospective validation study with technical notes. OBJECTIVE: This study aimed to validate a new ultra-low-dose full-spine protocol for reproducible Cobb angle measurements-the "nano-dose" protocol. SUMMARY OF BACKGROUND DATA: Scoliosis is a 3-dimensional (3D) deformity of the spine characterized by 3D clinical parameters. Nevertheless, 2D Cobb angle remains an essential and widely used radiologic measure in clinical practice. Repeated imaging is required for the assessment and follow-up of scoliosis patients. The resultant high dose of absorbed radiation increases the potential risk of developing radiation-induced cancer in such patients. Micro-dose radiographic imaging is already available in clinical practice, but the radiation dose delivered to the patient could be further reduced. METHODS: An anthropomorphic child phantom was used to establish an ultra-low-dose protocol in the EOS Imaging System still allowing Cobb angle measurements, defined as nano-dose. A group of 23 consecutive children presenting for scoliosis assessment, 12 years of age or younger, were assessed with standard-dose or micro-dose and additional nano-dose full-spine imaging modalities. Intraobserver and interobserver reliability of determining the reliability of 2D Cobb angle measurements was performed. The dosimetry was performed in the anthropomorphic phantom to confirm theoretical radiation dose reduction. RESULTS: A nano-dose protocol was established for reliable Cobb angle measurements. Dose area product with this new nano-dose protocol was reduced to 5 mGy×cm, corresponding to one sixth of the micro-dose protocol (30 mGy×cm) and <1/40th of the standard-dose protocol (222 mGy×cm). Theoretical dose reduction, for posteroanterolateral positioning was confirmed using phantom dosimetry. Our study showed good reliability and repeatability between the 2 groups. Cobb variability was <5 degrees from the mean using 95% confidence intervals. CONCLUSIONS: We propose a new clinically validated nano-dose protocol for routine follow-up of scoliosis patients before surgery, keeping the radiation dose at a bare minimum, while allowing for reproducible Cobb angle measurements.
Showing items related by title, author, creator and subject.
Microstructural characterization of annulus fibrosus by ultrasonography: a feasibility study with an in vivo and in vitro approach Article dans une revue avec comité de lectureLANGLAIS, Tristan; DESPRAIRIES, Pierre; PIETTON, Raphaël; ROHAN, Pierre-Yves; DUBOUSSET, Jean; MEAKIN, Judith R.; WINLOVE, Peter C.; VIALLE, Raphaël; SKALLI, Wafa; VERGARI, Claudio (Springer Verlag, 2019)The main function of the intervertebral disc is biomechanical function, since it must resist repetitive high loadings, while giving the spine its flexibility and protecting the spinal cord from over-straining. It partially ...
A reduced micro-dose protocol for 3D reconstruction of the spine in children with scoliosis: results of a phantom-based and clinically validated study using stereo-radiography Article dans une revue avec comité de lecturePEDERSEN, Peter H.; VERGARI, Claudio; ALZAKRI, Abdulmajeed; VIALLE, Raphaël; SKALLI, Wafa (Elsevier, 2019)Purpose The aim of this study was to validate the reproducibility of 3D reconstructions of the spine using a new reduced micro-dose protocol. Methods First, semi-quantitative image analysis was performed using an ...
3D quasi-automatic spine length assessment using low dose biplanar radiography after surgical correction in thoracic idiopathic scoliosis Article dans une revue avec comité de lectureLANGLAIS, T; VERGARI, Claudio; XAVIER, F; AL HAWSAWI, M; GAJNY, Laurent; VIALLE, Raphaël; SKALLI, Wafa; PIETTON, Raphaël (Elsevier BV, 2022)Background: As a leading cause of disability with a high societal and economic cost, it is crucial to better understand risk factors of neck pain and surgical complications. Getting subject-specific external loading is ...
Biplanar stereoradiography predicts pulmonary function tests in adolescent idiopathic scoliosis: a cross-sectional study Article dans une revue avec comité de lectureBOULOUSSA, Houssam; VERGARI, Claudio; HAEN, Thomas-Xavier; SKALLI, Wafa; VIALLE, Raphaël (Springer Verlag, 2019)Purpose Various spinal and rib cage parameters measured from complex examinations were found to be correlated with preoperative pulmonary function tests (PFT). The aim was to investigate the relationship between preoperative ...
Rib Cage Measurement Reproducibility Using Biplanar Stereoradiographic 3D Reconstructions in Adolescent Idiopathic Scoliosis Article dans une revue avec comité de lecturePIETTON, Raphael; BOULOUSSA, Houssam; VERGARI, Claudio; SKALLI, Wafa; VIALLE, Raphaël (Lippincott, Williams & WilkinsWolters kluwer, 2020)Study design: A reproducibility study of preoperative rib cage 3D measurements was conducted for patients with Adolescent Idiopathic Scoliosis (AIS). Objective: to assess the reliability of rib cage 3D reconstructions using ...