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Analyse théorique et expérimentale de la diffusion de la lumière générée par une diode électroluminescente dans des répliques tissulaires

Article dans une revue avec comité de lecture
Auteur
ccLE POMMELLEC, Jean Yves
211916 Laboratoire Angevin de Mécanique, Procédés et InnovAtion [LAMPA]
L'HUILLIER, Jean-Pierre
211916 Laboratoire Angevin de Mécanique, Procédés et InnovAtion [LAMPA]

URI
http://hdl.handle.net/10985/8471
DOI
10.1016/j.irbm.2011.10.002
Date
2011
Journal
Innovation and Research in BioMedical engineering

Résumé

The knowledge of the spatial distribution of light within a biological tissue exited by a light source (LASER or LED) is fundamental to achieve optimal photodynamic treatment. In this paper, we develop an analytical model relative to the diffuse fluence rate within a tissue-like medium irradiated by a continuous-wave light emitting diode (LED). The model is based on the two dimensional Fourier transform and applied to a homogeneous tissue slab. The total fluence rate along the axis of the medium was computed by adding the collimated and the diffuse components. The analytical solution was also used to study the depth evolution of the photon fluence rate as functions of the finite source beam size and the tissue optical parameters. Measurement results were performed using a tank filled with a liquid-simulating turbid medium (milk) illuminated with a LED beam. The experimental behaviour results agree with the theoretical predictions.

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Documents liés

Visualiser des documents liés par titre, auteur, créateur et sujet.

  • Assessment of the effective attenuation coefficient of scattering media illuminated by a LED array : Effect of the beam size 
    Communication avec acte
    ccLE POMMELLEC, Jean Yves; PIRON, Vianney; ASKOURA, Mohamed Lamine; L'HUILLIER, Jean-Pierre (The Society of Photo-Optical Instrumentation Engineers, 2015)
    The knowledge of the light fluence rate distribution inside a biological tissue irradiated by a Laser (or LED) is fundamental to achieve medical treatments. In this paper, we present a semi-analytical model based on the ...
  • Influence of the size and skin thickness of apple varieties on the retrieval of internal optical properties using Vis/NIR spectroscopy: A Monte Carlo-based study 
    Article dans une revue avec comité de lecture
    VAUDELLE, Fabrice; L'HUILLIER, Jean-Pierre (Elsevier, 2015)
    Visible/near-infrared spectroscopy is a well-established method to measure optical properties of tissues, assuming that a light propagation model can be used to recover absorption and reduced scattering coefficients from ...
  • Time-resolved optical fluorescence spectroscopy of heterogeneous turbid media with special emphasis on brain tissue structures including diseased regions: A sensitivity analysis 
    Article dans une revue avec comité de lecture
    VAUDELLE, Fabrice; L'HUILLIER, Jean-Pierre (Elsevier, 2013)
    Fluorescence-enhanced optical imaging based on near-infrared light provides a promising tool to differentiate diseased lesions from normal tissue. However, the measurement sensitivity of the fluorescence signals acquired ...
  • Light source distribution and scattering phase function influence light transport in diffuse multi-layered media 
    Article dans une revue avec comité de lecture
    VAUDELLE, Fabrice; L'HUILLIER, Jean-Pierre; ASKOURA, Mohamed Lamine (Elsevier, 2017)
    Red and near-Infrared light is often used as a useful diagnostic and imaging probe for highly scattering media such as biological tissues, fruits and vegetables. Part of diffusively reflected light gives interesting information ...
  • Experimental Study of Light Propagation in Apple Tissues Using a Multispectral Imaging System 
    Article dans une revue avec comité de lecture
    ASKOURA, Mohamed Lamine; VAUDELLE, Fabrice; L'HUILLIER, Jean-Pierre (MDPI, 2016)
    This work aimed at high lighting the role played by the skin in the light propagation through the apple flesh. A multispectral Visible-Near Infrared (Vis-NIR) steady-state imaging setup based on the use of four continuous ...

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