Biomechanical evaluation of a bioactive artificial anterior cruciate ligament
TypeArticles dans des revues avec comité de lecture
This study aimed to assess the biomechanical performance of a new generation of artificial ligament, which can be considered “bioactive” and “biointegrated,” implanted in sheep. Thirty sheep were implanted: 15 sheep received the artificial ligament grafted with a bioactive polymer (grafted) and 15 received the artificial ligament without a bioactive polymer (non-grafted). The animals were sacrificed 3 or 12 months after implantation. The knee kinematics, namely flexion-extension, anterior drawer, and varusvalgus tests, were evaluated using a fully characterized custom-made device. Afterward, the specimens were tested under uniaxial tension until failure. The flexion-extension showed significant differences between (grafted or non-grafted) artificial and native ligaments 3 months after implantation. This difference became non-significant 12 months postoperatively. The anterior tibial drawer was significantly increased 3 months after implantation and remained significantly different only for non-grafted ligament 12 months after implantation. Twelve months after implantation, the differences between grafted and non-grafted ligament biomechanical properties were significant in terms of stiffness. In terms of load to failure, grafted ligaments seem to have had slightly better performance than non-grafted ligaments 12 months postoperatively. Overall these results suggest that grafted artificial ligaments have slightly better biomechanical characteristics than non-grafted artificial ligaments 12 months after implantation in sheep.
Files in this item
Showing items related by title, author, creator and subject.
Biological and Biomechanical Evaluation of the Ligament Advanced Reinforcement System (LARS AC) in a Sheep Model of Anterior Cruciate Ligament Replacement: A 3-Month and 12-Month Study VIATEAU, Véronique; MANASSERO, Mathieu; ANAGOSTOU, Fani; GUERARD, Sandra; MITTON, David; MIGONNEY, Véronique (elsevier, 2013)PurposeThe purposes of this study were to assess tissue ingrowth within the Ligament Advanced Reinforcement System (LARS) artificial ligament (LARS AC; LARS, Arc sur Tille, France) and to study the biomechanical characteristics ...
The effect of polystyrene sodium sulfonate grafting on polyethylene terephthalate artificial ligaments on in vitro mineralisation and in vivo bone tissue integration VAQUETTE, Cédryck; VIATEAU, Véronique; GUERARD, Sandra; ANAGNOSTOU, Fani; MANASSERO, Mathieu; CASTNER, David G.; MIGONNEY, Véronique (elsevier, 2013)This study investigates the impact of polystyrene sodium sulfonate (PolyNaSS) grafting onto the osseointegration of a polyethylene terephthalate artificial ligament (Ligament Advanced Reinforcement System, LARS ) used for ...
Quantitative geometric analysis of rib, costal cartilage and sternum from childhood to teenagehood SANDOZ, Baptiste; BADINA, Alina; LAPORTE, Sébastien; LAMBOT, Karene; MITTON, David; SKALLI, Wafa (Springer, 2013)Better understanding of the effects of growth on children’s bones and cartilage is necessary for clinical and biomechanical purposes. The aim of this study is to define the 3D geometry of children’s rib cages: including ...
SANDOZ, Baptiste; LAPORTE, Sébastien; SKALLI, Wafa; MITTON, David (Taylor & Francis, 2010)In order to improve the reliability of children’s models, the aim of this study was to determine the subject-specific masses and 3D locations of the centres of mass (CoM) of body segments using biplanar X-rays. Previous ...
SIDELKEIR, Zaki; BADINA, Alina; BERMOND, François; MITTON, David; SKALLI, Wafa; SANDOZ, Baptiste (2013)The variability assessment of the rib bone mechanical properties during the growth process is still missing. These properties could not be obtained in vivo on children. Relationships have been obtained between Hounsfield ...